Nasolabial fold.
The fold from the side of the nose to the corner of the mouth. An anatomical structure that becomes more pronounced with mid-face volume loss; often treated indirectly via the cheek.
Nasolabial fold in the lexicon: why every face has one, how volume loss deepens it, treatment with hyaluronic acid directly or via the cheek, durability.
A closer look.
The nasolabial fold separates the cheek from the upper lip and is visible even in children when smiling – it is not a sign of ageing in itself. It becomes more pronounced when the fat compartments of the mid-face lose volume and descend; the cheek then 'hangs' over the fold.
That is why it is often not filled directly but the cause is addressed: some volume in the cheek and cheekbone area reduces the downward pull. With deep folds, direct cushioning is added – carefully, because the facial artery runs here; a blunt cannula lowers the risk.
Hyaluronic acid lasts six to twelve months in this mobile region. Very deep static folds can be softened, not removed. Botulinum toxin is not useful here because the fold is not created by muscle pull.
This lexicon entry is general information and does not replace the medical consultation required under German law (§ 630e BGB).
At a glance.
A question about Nasolabial fold? Send us a short WhatsApp message – we usually reply the same working day.
Ask via WhatsAppFrequently asked questions.
Why treat my cheek when the fold bothers me?
Because the fold looks deeper when the cheek descends. Supporting the mid-face often smooths the fold too.
Does Botox help with the nasolabial fold?
No, it is not an expression line.
Sources and further reading.
- NHS: Dermal fillers – patient information
- MPDG – German medical devices act (fillers are medical devices)
- BfArM – Federal Institute for Drugs and Medical Devices
- DGPRÄC – German Society of Plastic, Reconstructive and Aesthetic Surgeons
- § 630e BGB – duty to inform before treatment (German Civil Code)
- DGBT – German Society for Aesthetic Botulinum Toxin Therapy
- AWMF – German clinical practice guidelines
External links open in a new window; their operators are responsible for their content. Medical responsibility for this page: Katayoun Mostaghimi, specialist in general medicine. Last updated: 2026-10-05.
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