Smoking and skin.
After the sun, smoking is the second strongest avoidable factor in skin ageing. What happens in the tissue – and what quitting still achieves.

How smoking breaks down collagen, throttles blood flow and deepens lines around mouth and eyes – and why smokers heal more slowly after treatments.
Nicotine, oxygen, collagen.
Less oxygen, less repair: nicotine constricts the small blood vessels of the skin for hours after every cigarette. The skin receives less oxygen and fewer nutrients, waste products are removed more slowly. This shows as a dull, grey complexion and slower wound healing.
Collagen breakdown in fast-forward: tobacco smoke activates enzymes (matrix metalloproteinases) that break down collagen and elastin and at the same time inhibits new formation. Twin studies show: the smoking twin looks markedly older after ten years on average – with deeper lines around eyes, mouth and cheeks.
The typical signs: radial lines around the mouth ('smoker's lines') emphasised by pursing the lips, deepened crow's feet from squinting against smoke, hollow cheeks, uneven pigmentation and a leathery texture. Add an increased risk of skin cancer.
Consequences for treatments: in smokers hyaluronic acid and botulinum toxin often last less long, bruises take longer, and procedures relying on wound healing – microneedling, PRP – work less well. Before treatments at least a week without smoking is recommended, better more.
Quitting pays off at any age: blood flow normalises within weeks, the complexion brightens, collagen formation partly recovers. Existing lines do not disappear but deepen markedly more slowly. Anyone who quits gets more out of every treatment.
The essentials.
A question about Smoking and skin? Send us a short WhatsApp message – we usually reply the same working day.
Ask via WhatsAppImportant note.
This text is general information. It replaces neither a medical examination nor the consultation required before any treatment under German law (§ 630e BGB). Whether and which treatment is suitable for you can only be said after examination and consultation. No treatment results are promised.
Frequently asked questions.
Does this apply to e-cigarettes too?
Nicotine constricts vessels regardless of source; the additional combustion products are absent. Less harmful, not harmless.
Does Botox help with smoker's lines?
For fine lip lines the dose is very limited because mouth closure must be preserved. Skin boosters and skin-quality treatments are often more sensible here.
Sources and further reading.
- NHS: quit smoking
- Federal Centre for Health Education (BZgA)
- NHS: non-surgical cosmetic procedures
- Medical Association North Rhine – patient information
- § 630e BGB – duty to inform before treatment (German Civil Code)
- DGBT – German Society for Aesthetic Botulinum Toxin Therapy
- AWMF – German clinical practice guidelines
External links open in a new window; their operators are responsible for their content. Medical responsibility for this page: Katayoun Mostaghimi, specialist in general medicine. Last updated: 2026-10-15.
Talk to the physician.
Book on DoctolibOr simply call: +49 1520 8367711 · info@vivaderm.de
Or start with a consultation only: consultation appointment (€50, credited against a treatment)