Autoimmune disease and treatment.
Many patients with Hashimoto's or rheumatism ask whether Botox or fillers are excluded. The answer is nuanced – and mostly reassuring.

Hashimoto's, rheumatism, lupus, MS, myasthenia: which autoimmune diseases limit aesthetic treatments, which do not
Disease, activity, medication.
Hashimoto's thyroiditis: the most common autoimmune disease – and no obstacle to botulinum toxin, fillers or skin boosters if the thyroid is well controlled. There is no evidence of more complications.
Rheumatoid arthritis, psoriasis, Crohn's, colitis: treatment possible but with regard to medication. Under immunosuppressants (methotrexate, biologics, cortisone) infection risk is higher and wound healing delayed – fillers with special care, microneedling and PRP only in stable phases. No elective treatments during an active flare.
Lupus, scleroderma, dermatomyositis: here the skin itself is affected. Fillers can trigger reactions in active phases; treatment only in consultation with the treating rheumatologist and in remission. Botulinum toxin is mostly unproblematic.
Myasthenia gravis, Lambert-Eaton syndrome, ALS: these diseases affect signal transmission to the muscle – exactly where botulinum toxin acts. It is contraindicated here. Multiple sclerosis, by contrast, is no exclusion; botulinum toxin is even used therapeutically against spasticity in MS.
Fillers and 'autoimmune reactions': very rarely, delayed nodules appear weeks to months after fillers, often after infections or vaccinations. With an existing autoimmune disease the risk may be slightly higher. It is well treatable – but a reason for consent discussion and restrained amounts.
Important: state diagnosis, current medicines and the last flare in the consent talk. If unsure, the practice obtains the agreement of the treating specialist. No disclosure is too unimportant.
The essentials.
A question about Autoimmune diseases? Send us a short WhatsApp message – we usually reply the same working day.
Ask via WhatsAppImportant note.
This text is general information. It replaces neither a medical examination nor the consultation required before any treatment under German law (§ 630e BGB). Whether and which treatment is suitable for you can only be said after examination and consultation. No treatment results are promised.
Frequently asked questions.
I take methotrexate – may I have fillers?
In principle yes, in a stable phase and with strict hygiene. The decision is made individually after consultation.
Should I tell my rheumatologist?
Recommended. They know your disease activity and can judge whether the timing fits.
Sources and further reading.
- § 630e BGB – duty to inform before treatment (German Civil Code)
- GOÄ – German scale of medical fees (official text)
- § 11 HWG – ban on before/after images and advertising promises
- Professional code of the Medical Association North Rhine
- NHS: non-surgical cosmetic procedures
- Medical Association North Rhine – patient information
- DGBT – German Society for Aesthetic Botulinum Toxin Therapy
External links open in a new window; their operators are responsible for their content. Medical responsibility for this page: Katayoun Mostaghimi, specialist in general medicine. Last updated: 2026-10-05.
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